Challenges and Solutions in the Pharmaceutical Industry

Challenge ➢ Reproducible dosing despite variations in the substance

Pharmaceutical raw materials are often sensitive: flow behavior, bulk density, particle size distribution, and moisture content can vary from batch to batch. In practice, this leads to unstable material flows, dosing deviations, and increased control and operational effort—especially in continuous processes, where deviations have a direct impact on quality.

Added to this is the variety of media: bulk solids, powders, pastes, and liquids place very different demands on discharge mechanisms, control systems, and refill processes. Tailored control solutions must accurately account for these differences to ensure the process remains stable and parameter changes can be carried out in a controlled manner.

The DEMIC Solution

DEMIC offers tailor-made solutions for the continuous dosing of bulk materials, powders, pastes, and liquids—with control concepts that monitor the actual process conditions and actively compensate for deviations.
The dosing control system is designed as a key technology to ensure precise and consistent mixing and dispensing processes—even in applications within the chemical and pharmaceutical industries.

Challenge ➢ Precisely dosing the smallest amounts of active ingredients

Many pharmaceutical applications require very small dosing volumes—for example, when handling highly active ingredients, additives, or concentrates. In these cases, it is not only nominal accuracy that matters, but above all repeatability and process stability: even the slightest fluctuations have a direct impact on specifications and quality.

The challenge becomes particularly demanding when very small quantities are combined with varying material properties, dosing interruptions (e.g., during refilling), or fluctuating process conditions. In such cases, dosing and control technology is needed that detects deviations in real time and compensates for them reliably.

THE DEMIC SOLUTION

Microdosing plays a central role in applications involving very small quantities: The goal is to dispense extremely small volumes of liquids or powders with high accuracy and repeatability—which is particularly relevant for the pharmaceutical industry.
In addition, gravimetric dosing concepts and intelligent control ensure that the actual mass flow remains stable and that disturbances are automatically compensated for—ensuring reproducible results even in sensitive processes.

Solutions: Intelligent Dosing and Control Technology for Stable Pharmaceutical Processes

Precision-coordinated dosing, weighing, and control systems are crucial for pharmaceutical production processes. Both continuous dosing and batch weighing must be reliably controlled to ensure that formulations remain reproducible and process windows can be maintained within stable limits. DEMIC relies on a modular, holistic system concept—from dosing and control to operation.

The combination of suitable dosing technology, high-resolution weight measurement, and powerful process control results in robust solutions that accommodate a wide range of media (powders, bulk materials, pastes, liquids) and can be flexibly adapted to changes in equipment and formulations.

Your Contacts

Björn Demmer

Partner - Managing Director

PHONE: 02247 918 90
EMAIL: bdemmer(at)demic-datentechnik.de

Heinz Demmer

Partner - Managing Director

PHONE: 02247 918 90
EMAIL: hdemmer(at)demic-datentechnik.de

FAQs About the Pharmaceutical Industry

Because product quality and specifications depend directly on precise mixing and dosing ratios—even small deviations can affect concentration and reproducibility.

DEMIC offers solutions for the continuous dosing of bulk materials, powders, pastes, and liquids.

Microdosing aims to dispense extremely small volumes of liquids or powders with high accuracy and repeatability—particularly in the pharmaceutical industry.

Intelligent control stabilizes the dosing process by detecting and actively compensating for variations in material flow—which is particularly important when dealing with varying batches and sensitive powders.
 

Dosing control enables precise and consistent mixing and dispensing of materials, making it essential for product quality and process reliability.

Yes. DEMIC focuses on solutions for continuous dosing and batch weighing as part of comprehensive system solutions.

In continuous operations, refill processes are integrated into the process control system to ensure that the mass flow remains stable and to prevent sudden fluctuations.
 

DEMIC develops comprehensive system solutions that are modular in design and can be integrated into existing plant designs—depending on the process and interfaces.

When the dosing unit, control system, drive technology, load cell measurement, and user interface work together seamlessly, process stability increases and implementing parameter and recipe changes becomes significantly easier.

Through customized dosing and control solutions that continuously monitor, evaluate, and stabilize the dosing process.